Ultimate-E 60 Fish Gelatin Gelcaps by Thorne Research is a premium mixed-tocopherol formula that provides all the natural forms of vitamin E without the addition of soy oil. This product is a good source of gamma tocopherol, which offers numerous benefits for overall health.

With its unique blend of natural isomers of vitamin E, Ultimate-E offers protection against free radicals and products of oxygenation, including lipid peroxides and singlet oxygen radicals. The gamma-tocopherol in this formula inhibits the enzyme cyclooxygenase, while alpha-tocopherol does not have a significant effect on this enzyme.

Human studies comparing diets supplemented with both gamma- and alpha-tocopherols to diets supplemented primarily with alpha-tocopherol found more DNA protection in the mixed-tocopherol group. This suggests that the naturally occurring ratio of tocopherols in Ultimate-E provides a more potent antioxidant effect than alpha-tocopherol alone.

Vitamin E is an essential antioxidant that plays a vital role in overall antioxidant capacity in the blood and tissues. Numerous clinical studies have shown its benefits for the cardiovascular system. Recent studies focusing on mixed tocopherols have indicated that they have a stronger inhibitory effect on lipid peroxidation than alpha-tocopherol alone, further highlighting the potent antioxidant effect of mixed tocopherols.

Unlike many vitamin E products on the market, Thorne's Ultimate-E is not diluted with soy oil. The pure undiluted vitamin E is extracted from a mixture of vegetable oils, including soy oil, but any potentially allergenic soy residues are removed during the distillation process. Each batch of Ultimate-E is standardized to contain 500 IU of alpha-tocopherol per capsule.

One gelcap of Ultimate-E contains a powerful dose of vitamin E, with 500 IU of d-Alpha Tocopherol from 1000 mg mixed tocopherols. The typical profile of Ultimate-E includes d-Alpha Tocopherol, Beta tocopherol, Gamma tocopherol, and Delta tocopherol. These tocopherols may vary slightly from batch to batch, but each batch is adjusted to achieve the standardized amount of alpha-tocopherol.

The gelcaps are made from fish gelatin derived from tilapia and are free from wheat gluten, corn, yeast, soy, egg, dairy products, artificial colors, sweeteners, and flavors. Ultimate-E is also free from lactose, palmitic acid, magnesium, calcium, and vegetable stearates.

It is important to note that this product should be avoided by individuals with a history of hypersensitivity to any of its ingredients. Pregnant or nursing individuals should consult with a healthcare practitioner before using this product. As of the publication date, there are no known adverse interactions or contraindications associated with Ultimate-E.